2016 |
Soto, C; Saavedra, R; Toral, M I; Nacaratte, F; Poza, C Preliminary Studies for Ciclopirox Olamine Determination by Thermal Lens Spectrophotometry Artículo de revista Microchemical Journal, 129 , pp. 36-40, 2016, ISSN: 0026-265x. Resumen | Enlaces | BibTeX | Etiquetas: antimycotic, chromatography, ciclopirox derivatization, flow lens olamine, polarographic-determination, precolumn spectrometry, spectroscopy, thermal @article{soto2016preliminary, title = {Preliminary Studies for Ciclopirox Olamine Determination by Thermal Lens Spectrophotometry}, author = { C. Soto and R. Saavedra and M.I. Toral and F. Nacaratte and C. Poza}, url = {/brokenurl#<Go to ISI>://WOS:000382595300006}, doi = {10.1016/j.microc.2016.06.004}, issn = {0026-265x}, year = {2016}, date = {2016-01-01}, journal = {Microchemical Journal}, volume = {129}, pages = {36-40}, publisher = {2016 Elsevier B.V.}, abstract = {The spectrophotometric kinetic methods are broadly used in the determination of drugs in several types of matrices. Thermal Lens Spectrometry (TLS) has demonstrated to be a sensitive indirect spectrophotometric technique used in the field of applied sciences, such as environmental and biochemical sciences. Ciclopirox olamine (OM) is a synthetic fungicide that inhibits the growth of pathogenic dermatophytes. This work presents the results of CXO determination by TLS, through a kinetic method, based on the CXO oxidation with KMnO4 in alkaline medium to form manganate (MnO42-). The Thermal Lens (TL) effect was generated by a He-Ne laser (TEM00, 20 mW, 632 nm). The TLS measurements were performed on a single beam assembly with a lens of f = 7.5 cm focal distance and 10 Hz modulation frequency. The TL signal from the detector was acquired for each sample. The optimization was at 30 min reaction time, KMnO4 8.0 . 10(-4) mol L-1 and Na2SO4 0.6 mol L-1. Under these conditions a calibration curve was constructed. The analytical features were LOD = 3.40 mu mol L-1 and LOQ = 113 mu mol L-1. To examine accuracy and reliability, the determination method was successfully applied in tap water samples where known amounts of CXO were spiked.}, keywords = {antimycotic, chromatography, ciclopirox derivatization, flow lens olamine, polarographic-determination, precolumn spectrometry, spectroscopy, thermal}, pubstate = {published}, tppubtype = {article} } The spectrophotometric kinetic methods are broadly used in the determination of drugs in several types of matrices. Thermal Lens Spectrometry (TLS) has demonstrated to be a sensitive indirect spectrophotometric technique used in the field of applied sciences, such as environmental and biochemical sciences. Ciclopirox olamine (OM) is a synthetic fungicide that inhibits the growth of pathogenic dermatophytes. This work presents the results of CXO determination by TLS, through a kinetic method, based on the CXO oxidation with KMnO4 in alkaline medium to form manganate (MnO42-). The Thermal Lens (TL) effect was generated by a He-Ne laser (TEM00, 20 mW, 632 nm). The TLS measurements were performed on a single beam assembly with a lens of f = 7.5 cm focal distance and 10 Hz modulation frequency. The TL signal from the detector was acquired for each sample. The optimization was at 30 min reaction time, KMnO4 8.0 . 10(-4) mol L-1 and Na2SO4 0.6 mol L-1. Under these conditions a calibration curve was constructed. The analytical features were LOD = 3.40 mu mol L-1 and LOQ = 113 mu mol L-1. To examine accuracy and reliability, the determination method was successfully applied in tap water samples where known amounts of CXO were spiked. |
2015 |
Duffau, B; Camargo, C; Cassels, B K; Kogan, M; Fuentes, E Analysis of a New Potent Hallucinogen, 25-B-Nbome, in Blotters by High-Performance Thin-Layer Chromatography Artículo de revista Jpc-Journal of Planar Chromatography-Modern Tlc, 28 (5), pp. 395-397, 2015, ISSN: 0933-4173. Enlaces | BibTeX | Etiquetas: blotters, chromatography, hallucinogens, high-performance quantitation thin-layer validation @article{duffau2015analysis, title = {Analysis of a New Potent Hallucinogen, 25-B-Nbome, in Blotters by High-Performance Thin-Layer Chromatography}, author = { B. Duffau and C. Camargo and B.K. Cassels and M. Kogan and E. Fuentes}, url = {/brokenurl#<Go to ISI>://WOS:000363410100009}, doi = {10.1556/1006.2015.28.5.9}, issn = {0933-4173}, year = {2015}, date = {2015-01-01}, journal = {Jpc-Journal of Planar Chromatography-Modern Tlc}, volume = {28}, number = {5}, pages = {395-397}, keywords = {blotters, chromatography, hallucinogens, high-performance quantitation thin-layer validation}, pubstate = {published}, tppubtype = {article} } |
2016 |
Preliminary Studies for Ciclopirox Olamine Determination by Thermal Lens Spectrophotometry Artículo de revista Microchemical Journal, 129 , pp. 36-40, 2016, ISSN: 0026-265x. |
2015 |
Analysis of a New Potent Hallucinogen, 25-B-Nbome, in Blotters by High-Performance Thin-Layer Chromatography Artículo de revista Jpc-Journal of Planar Chromatography-Modern Tlc, 28 (5), pp. 395-397, 2015, ISSN: 0933-4173. |