Publicaciones 2011-2020

@article{RN29d,
title = {Influence of Tio2 on Prebiotic Thermal Synthesis of the Gly-Gln Polymer},
author = { P. Leyton and R. Saladino and C. Crestini and M. Campos-Vallette and C. Paipa and A. Berrios and S. Fuentes and R.A. Zarate},
url = {/brokenurl#<Go to ISI>://WOS:000304150300004},
doi = {10.1007/s00726-011-0939-6},
issn = {0939-4451},
year = {2012},
date = {2012-01-01},
journal = {Amino Acids},
volume = {42},
number = {6},
pages = {2079-2088},
abstract = {The role of the titanium dioxide (rutile and anatase) with and without room light on the thermal synthesis of the glycine--glutamine (Gly-Gln) polymer is described. The efficiency in percentage of polymerization with room light was increased in 6% in the presence of rutile and in 23% in the presence of anatase. The thermal synthesis in the molten state was carried out in the absence and presence of both oxides. In all cases, the vibrational spectra showed characteristic group frequencies corresponding to a polypeptide structure. No spectral differences were observed by room light effect on the polymer on rutile. However, the polymer obtained in the presence of anatase and room light shows spectral changes associated with the formation of shorter new abundant and conformationally different species compared with the original polymer. The SEM-EDX characterization of the solid phase involved in the thermal synthesis showed that the morphology of the polypeptide is different in the presence of rutile compared to anatase. The SDS-PAGE and GPC results suggest that smaller chains are formed in the presence of both oxides and the distribution of the size and weight of each polymer molecule is completely different when the condensation is performed in the presence of anatase or rutile. Nuclear magnetic resonance analyses confirmed the incorporation of both Gly and Gln residues in the polymers, with a prevalence of Gly. Both possible sequences -GlyGln- and -GlnGly- were also detected.},
keywords = {amino-acids, chemistry, condensation conditions, crystalline diketopiperazine, dioxide, dynamics, earth formation ft-ir glutamic glycine, peptide prebiotic primitive reaction, self-disproportionation, spectra, spectroscopy, synthesis, thermal titanium vibrational},
pubstate = {published},
tppubtype = {article}
}

@article{RN27d,
title = {Influence of Aluminum Oxide on the Prebiotic Thermal Synthesis of Gly-Glu-(Gly-Glu)(N) Polymer},
author = { P. Leyton and R.A. Zarate and S. Fuentes and C. Paipa and J.S. Gomez-Jeria and Y. Leyton},
url = {/brokenurl#<Go to ISI>://WOS:000290194500006},
doi = {10.1016/j.biosystems.2011.01.008},
issn = {0303-2647},
year = {2011},
date = {2011-01-01},
journal = {Biosystems},
volume = {104},
number = {2-3},
pages = {118-126},
publisher = {2011 Elsevier Ireland Ltd.},
abstract = {The effect of the aluminum oxide on the thermal synthesis of the glycine-glutamic acid (Gly-Glu-(Gly-Glu)(n) polymer is described. The thermal synthesis in the molten state was carried out in the absence and presence of the oxide. In both cases, the vibrational spectra showed characteristic group frequencies corresponding predominantly to a Gly-Glu-(Gly-Glu)(n) sequence in the polymeric structure. The theoretical spectral data support the experimental proposed Gly-Glu-(Gly-Glu)(n) sequence for the polymer. The SEM-EDX characterization of the solid phase involved in the thermal synthesis showed that the aluminum oxide participates as a site for nucleation and growth of the polymer, explaining the increase of 25% efficiency in the presence of aluminum oxide. Electrophoresis data show shorter polypeptide chains in the presence of aluminum oxide.},
keywords = {amino-acid-sequences, analysis, bond chemistry, conditions, crystalline diketopiperazine, earth formation formation, glutamic glycine ir-spectra, peptide prebiotic primitive pyroglutamic reaction, spectroscopy, synthesis, thermal vibrational},
pubstate = {published},
tppubtype = {article}
}