2015 |
Vera, A M; Carcamo, J J; Aliaga, A E; Gomez-Jeria, J S; Kogan, M J; Campos-Vallette, M Interaction of the Clpffd Peptide with Gold Nanospheres. A Raman, Surface Enhanced Raman Scattering and Theoretical Study Artículo de revista Spectrochimica Acta Part a-Molecular and Biomolecular Spectroscopy, 134 , pp. 251-256, 2015, ISSN: 1386-1425. Resumen | Enlaces | BibTeX | Etiquetas: alzheimer-disease, anti-aggregation approximations, assemblies, beta-amyloid, calculations, clpffd extended hartree-fock htickel molecular-orbital nanoparticles, of peptide peptide, protein, sers, silver, spectroscopy, stability theories, theory type @article{RN262, title = {Interaction of the Clpffd Peptide with Gold Nanospheres. A Raman, Surface Enhanced Raman Scattering and Theoretical Study}, author = { A.M. Vera and J.J. Carcamo and A.E. Aliaga and J.S. Gomez-Jeria and M.J. Kogan and M. Campos-Vallette}, url = {/brokenurl#<Go to ISI>://WOS:000342718700034}, doi = {10.1016/j.saa.2014.06.116}, issn = {1386-1425}, year = {2015}, date = {2015-01-01}, journal = {Spectrochimica Acta Part a-Molecular and Biomolecular Spectroscopy}, volume = {134}, pages = {251-256}, publisher = {2014 Elsevier B.V.}, abstract = {In a previous work we demonstrated that toxic aggregates of the protein beta-amyloid (ATA beta) involved in the Alzheimer's disease (AD) can be destabilized upon electromagnetic irradiation of the peptide Cys-Leu-Pro-Phe-Phe-Asp (CLPFFD) adsorbed on gold nanospheres (AuNSs). For a selective recognition of the therapeutic target (i.e. ATA beta) of AD by the conjugates peptide-nanoparticle it is relevant to understand how the interaction between attached ligands and nanoparticles occurs. In this work a surface enhanced Raman scattering spectroscopy (SERS) study of the interactions of CLPFFD with AuNSs of 10 nm average diameter was carried out. The SERS data suggest that phenylalanine displays its aromatic ring coplanar to the surface which is supported by theoretical data obtained from molecular mechanics (MM) and Extended Huckel Theory (EHT) calculations.}, keywords = {alzheimer-disease, anti-aggregation approximations, assemblies, beta-amyloid, calculations, clpffd extended hartree-fock htickel molecular-orbital nanoparticles, of peptide peptide, protein, sers, silver, spectroscopy, stability theories, theory type}, pubstate = {published}, tppubtype = {article} } In a previous work we demonstrated that toxic aggregates of the protein beta-amyloid (ATA beta) involved in the Alzheimer's disease (AD) can be destabilized upon electromagnetic irradiation of the peptide Cys-Leu-Pro-Phe-Phe-Asp (CLPFFD) adsorbed on gold nanospheres (AuNSs). For a selective recognition of the therapeutic target (i.e. ATA beta) of AD by the conjugates peptide-nanoparticle it is relevant to understand how the interaction between attached ligands and nanoparticles occurs. In this work a surface enhanced Raman scattering spectroscopy (SERS) study of the interactions of CLPFFD with AuNSs of 10 nm average diameter was carried out. The SERS data suggest that phenylalanine displays its aromatic ring coplanar to the surface which is supported by theoretical data obtained from molecular mechanics (MM) and Extended Huckel Theory (EHT) calculations. |
2013 |
Benavente, E; Lozano, H; González, G Fabrication of Copper Nanoparticles: Advances in Synthesis, Morphology Control, and Chemical Stability Artículo de revista Recent Patents on Nanotechnology, 7 (2), pp. 108-132, 2013, ISSN: 1872-2105. Resumen | Enlaces | BibTeX | Etiquetas: assemblies, colloidal copper copper, cu enhanced fabrication irradiation, laser metal micelles, nanocopper, nanoparticle nanoparticles, nanosized particles, polyol process, raman-scattering, reduction, reverse size synthesis, thermal @article{RN133, title = {Fabrication of Copper Nanoparticles: Advances in Synthesis, Morphology Control, and Chemical Stability}, author = { E. Benavente and H. Lozano and G. Gonz\'{a}lez}, url = {/brokenurl#<Go to ISI>://WOS:000327780100002}, doi = {10.2174/1872210511307020002}, issn = {1872-2105}, year = {2013}, date = {2013-01-01}, journal = {Recent Patents on Nanotechnology}, volume = {7}, number = {2}, pages = {108-132}, abstract = {Metal nanoparticles have attracted great interest particularly because of the size dependence of physical and chemical properties and its enormous technological potential. Although most pioneering advancements refers to gold and silver, more recently there is growing interest in nanoparticles of copper, mostly due to its relatively low cost, which could allow the use of these small metal objects in large-scale nanotechnology applications, for example, antiseptics materials and metallic inks. However, the manufacture of copper nanoparticles stable in air with controlled size and shape has been a major challenge because of the relatively high reactivity of this element. Great efforts in getting the basic knowledge and synthesis know-how has gone into finding better ways to produce particles protected against oxidation and self-aggregation under normal conditions. In this review article, we briefly discuss a number of selected papers and recent patents on procedures and other issues related to the fabrication of copper nanoparticles.}, keywords = {assemblies, colloidal copper copper, cu enhanced fabrication irradiation, laser metal micelles, nanocopper, nanoparticle nanoparticles, nanosized particles, polyol process, raman-scattering, reduction, reverse size synthesis, thermal}, pubstate = {published}, tppubtype = {article} } Metal nanoparticles have attracted great interest particularly because of the size dependence of physical and chemical properties and its enormous technological potential. Although most pioneering advancements refers to gold and silver, more recently there is growing interest in nanoparticles of copper, mostly due to its relatively low cost, which could allow the use of these small metal objects in large-scale nanotechnology applications, for example, antiseptics materials and metallic inks. However, the manufacture of copper nanoparticles stable in air with controlled size and shape has been a major challenge because of the relatively high reactivity of this element. Great efforts in getting the basic knowledge and synthesis know-how has gone into finding better ways to produce particles protected against oxidation and self-aggregation under normal conditions. In this review article, we briefly discuss a number of selected papers and recent patents on procedures and other issues related to the fabrication of copper nanoparticles. |
2015 |
Interaction of the Clpffd Peptide with Gold Nanospheres. A Raman, Surface Enhanced Raman Scattering and Theoretical Study Artículo de revista Spectrochimica Acta Part a-Molecular and Biomolecular Spectroscopy, 134 , pp. 251-256, 2015, ISSN: 1386-1425. |
2013 |
Fabrication of Copper Nanoparticles: Advances in Synthesis, Morphology Control, and Chemical Stability Artículo de revista Recent Patents on Nanotechnology, 7 (2), pp. 108-132, 2013, ISSN: 1872-2105. |