Publicaciones 2011-2020

@article{RN403,
title = {Inhibiting Pathogen Surface Adherence by Multilayer Polyelectrolyte Films Functionalized with Glucofuranose Derivatives},
author = { V. Villalobos and A. Leiva and H. Rios and J. Pavez and C.P. Silva and M. Ahmar and Y. Queneau and J.M. Blamey and F.P. Chavez and M. Urz\'{u}a},
url = {/brokenurl#<Go to ISI>://WOS:000442706600064},
doi = {10.1021/acsami.8b03605},
issn = {1944-8244},
year = {2018},
date = {2018-01-01},
journal = {Acs Applied Materials & Interfaces},
volume = {10},
number = {33},
pages = {28147-28158},
abstract = {Inhibiting pathogenic bacterial adherence on surfaces is an ongoing challenge to prevent the development of biofilms. Multilayer polyelectrolyte films are feasible antibacterial materials. Here, we have designed new films made of carbohydrate polyelectrolytes to obtain antibacterial coatings that prevent biofilm formation. The polyelectrolyte films were constructed from poly(maleic anhydride-alt-styrene) functionalized with glucofuranose derivatives and quaternized poly(4-vinylpyridine) N-alkyl. These films prevent Pseudomonas aeruginosa and Salmonella Typhimurium, two important bacterial contaminants in clinical environments, from adhering to surfaces. When the film was composed of more than 10 layers, the bacterial population was greatly reduced, while the bacteria remaining on the film were morphologically damaged, as atomic force microscopy revealed. The antibacterial capacity of the polyelectrolyte films was determined by the combination of thickness, wettability, surface energy, and most importantly, the conformation that polyelectrolytes adopt the function of nature of the carbohydrate group. This polyelectrolyte film constitutes the first green approach to preventing pathogenic bacterial surface adherence and proliferation without killing the bacterial pathogen.},
keywords = {antibacterial bacterial, biofilm biomaterials, carbohydrate challenges coatings, construction, formation, inhibition, mechanisms, p. polyelectrolytes, resistance, s. surfaces, typhimurium},
pubstate = {published},
tppubtype = {article}
}

@article{bravo2016theoretical,
title = {A Theoretical Analysis of the Relationship between the Electronic Structure of Indole Derivatives and Their Phytotoxicity against Lactuca Sativa Seeds},
author = { H. Bravo and B. Weiss-Lopez and J. Valdebenito-Gamboa and J.S. Gomez-Jeria},
url = {/brokenurl#<Go to ISI>://WOS:000410566700271},
issn = {0975-8585},
year = {2016},
date = {2016-01-01},
journal = {Research Journal of Pharmaceutical Biological and Chemical Sciences},
volume = {7},
number = {2},
pages = {792-798},
abstract = {Allelopathic effects of a chemical compound strongly depends on the target species, dose or concentration employed, structure of the molecule and physical properties, such as water solubility, lipophilicity and others. In this work, we present the results of a preliminary quantum-chemical analysis of the possible relationships between the electronic structure of a series of indole derivatives and the percentage of germination inhibition (I) of Lactuca Sativa seeds. The results allow predicting phytotoxicity activity of these compounds, the structural features of an ideal indole derivative, as well as some structural characteristics of the active site.},
keywords = {alkaloids allelochemicals, allelopathy, barley derivatives, gramine, indole lactuca management, qsar, resistance, sativa, seedlings, weed},
pubstate = {published},
tppubtype = {article}
}