Publicaciones 2011-2020

@article{RN354,
title = {Synthesis of Bifunctional Receptor for Fluoride and Cadmium Based on Calix[4]Arene with Thiourea Moieties},
author = { C. Quiroga-Campano and H. Gomez-Machuca and S. Moris and P. Jara and J.R. De La Fuente and H. Pessoa-Mahana and C. Jullian and C. Saitz-Barria},
url = {/brokenurl#<Go to ISI>://WOS:000401593400017},
doi = {10.1016/j.molstruc.2017.03.089},
issn = {0022-2860},
year = {2017},
date = {2017-01-01},
journal = {Journal of Molecular Structure},
volume = {1141},
pages = {133-141},
publisher = {2017 Elsevier B.V.},
abstract = {A new calix[4]arene thiourea derivative bearing a benzothiazolyl moiety (L) was synthetized and characterized by single crystal X-ray, NMR and ESI-TOF. The binding ability of the bifunctional receptor towards several ions was investigated in acetonitrile by means of UV-Visible and NMR spectroscopy. The UV-Vis studies of receptor L demonstrated a stoichiometry of 1:1 for all ions studied. Also, recognize selectively F- and Cd2+ with a detection limit of 97 and 37 mu M, respectively., Also, H-1 NMR titration of receptor L indicated that both thiourea bridge and phenolic hydroxyl functional groups played a critical role in the binding of F- and Cd2+ ions. H-1 NMR spectrum showed that receptor L has a flattened-cone conformation in solution that changes to a cone conformation in the presence of fluoride while cadmium maintained the initial conformation.},
keywords = {bearing benzothiazole, cadmium, calix[4]arene, chemosensor, complexation, conformation, detection, fluorescent, fluoride, heterocycles, highly ions lower recognition, rim, selective thiourea},
pubstate = {published},
tppubtype = {article}
}

@article{RN266,
title = {Heterocyclic Curcumin Derivatives of Pharmacological Interest: Recent Progress},
author = { M. Martinez-Cifuentes and B. Weiss-Lopez and L.S. Santos and R. Araya-Maturana},
url = {/brokenurl#<Go to ISI>://WOS:000355570800003},
doi = {10.2174/1568026615666150427111837},
issn = {1568-0266},
year = {2015},
date = {2015-01-01},
journal = {Current Topics in Medicinal Chemistry},
volume = {15},
number = {17},
pages = {1663-1672},
abstract = {Curcumin, a natural yellow polyphenol, is isolated from the herb Curcuma longa L. (turmeric), a member of the ginger family. It has been extensively studied due to their multiple pharmacological properties. Nevertheless, curcumin has disadvantages such as poor water solubility, poor bioavailability and rapid metabolism, which has prompted the search for analogues that overcome these shortcomings while maintaining or improving their good pharmacological properties. Among the main curcumin analogues that have been developed, the heterocyclic curcuminoids show a high interest. In this review, we describe recent progress in the synthesis and pharmacological properties of new heterocyclic curcumin derivatives. The most recent developments in anti-cancer, anti-Alzheimer, anti-bacterial and anti-oxidants heterocyclic curcumin derivatives are covered.},
keywords = {alzheimer, analogs, antibacterial, antiinflammatory antioxidant, antioxidants, apoptosis, bioavailability, cancer, curcumin, cytotoxicity, heterocycles, in-vitro, inhibitors molecular properties, targets},
pubstate = {published},
tppubtype = {article}
}