Publicaciones 2011-2020

@article{RN354,
title = {Synthesis of Bifunctional Receptor for Fluoride and Cadmium Based on Calix[4]Arene with Thiourea Moieties},
author = { C. Quiroga-Campano and H. Gomez-Machuca and S. Moris and P. Jara and J.R. De La Fuente and H. Pessoa-Mahana and C. Jullian and C. Saitz-Barria},
url = {/brokenurl#<Go to ISI>://WOS:000401593400017},
doi = {10.1016/j.molstruc.2017.03.089},
issn = {0022-2860},
year = {2017},
date = {2017-01-01},
journal = {Journal of Molecular Structure},
volume = {1141},
pages = {133-141},
publisher = {2017 Elsevier B.V.},
abstract = {A new calix[4]arene thiourea derivative bearing a benzothiazolyl moiety (L) was synthetized and characterized by single crystal X-ray, NMR and ESI-TOF. The binding ability of the bifunctional receptor towards several ions was investigated in acetonitrile by means of UV-Visible and NMR spectroscopy. The UV-Vis studies of receptor L demonstrated a stoichiometry of 1:1 for all ions studied. Also, recognize selectively F- and Cd2+ with a detection limit of 97 and 37 mu M, respectively., Also, H-1 NMR titration of receptor L indicated that both thiourea bridge and phenolic hydroxyl functional groups played a critical role in the binding of F- and Cd2+ ions. H-1 NMR spectrum showed that receptor L has a flattened-cone conformation in solution that changes to a cone conformation in the presence of fluoride while cadmium maintained the initial conformation.},
keywords = {bearing benzothiazole, cadmium, calix[4]arene, chemosensor, complexation, conformation, detection, fluorescent, fluoride, heterocycles, highly ions lower recognition, rim, selective thiourea},
pubstate = {published},
tppubtype = {article}
}

@article{RN194,
title = {Coumarin-Based Fluorescent Probes for Dual Recognition of Copper(Ii) and Iron(Iii) Ions and Their Application in Bio-Imaging},
author = { O. Garcia-Beltran and B.K. Cassels and C. Perez and N. Mena and M. Nunez and N.P. Martinez and P. Pavez and M.E. Aliaga},
url = {/brokenurl#<Go to ISI>://WOS:000336039100075},
doi = {10.3390/s140101358},
issn = {1424-8220},
year = {2014},
date = {2014-01-01},
journal = {Sensors},
volume = {14},
number = {1},
pages = {1358-1371},
abstract = {Two new coumarin-based "turn-off" fluorescent probes, (E)-3-((3,4-dihydroxybenzylidene)amino)-7-hydroxy-2H-chromen-2-one (BS1) and (E)-3-((2,4-dihydroxybenzylidene)amino)-7-hydroxy-2H-chromen-2-one (BS2), were synthesized and their detection of copper(II) and iron(III) ions was studied. Results show that both compounds are highly selective for Cu2+ and Fe3+ ions over other metal ions. However, BS2 is detected directly, while detection of BS1 involves a hydrolysis reaction to regenerate 3-amino-7-hydroxycoumarin (3) and 3,4-dihydroxybenzaldehyde, of which 3 is able to react with copper(II) or iron(III) ions. The interaction between the tested compounds and copper or iron ions is associated with a large fluorescence decrease, showing detection limits of ca. 10(-5) M. Preliminary studies employing epifluorescence microscopy demonstrate that Cu2+ and Fe3+ ions can be imaged in human neuroblastoma SH-SY5Y cells treated with the tested probes.},
keywords = {bio-imaging, chemosensor, coumarin-based cu2+ cu2+, design, fe3+ fluorescence ion, probes, sensor sensors, turn-off},
pubstate = {published},
tppubtype = {article}
}

@article{RN125,
title = {Design, Synthesis and Cellular Dynamics Studies in Membranes of a New Coumarin-Based "Turn-Off" Fluorescent Probe Selective for Fe2+},
author = { O. Garcia-Beltran and N. Mena and O. Yanez and J. Caballero and V. Vargas and M. Nunez and B.K. Cassels},
url = {/brokenurl#<Go to ISI>://WOS:000325121800007},
doi = {10.1016/j.ejmech.2013.06.022},
issn = {0223-5234},
year = {2013},
date = {2013-01-01},
journal = {European Journal of Medicinal Chemistry},
volume = {67},
pages = {60-63},
publisher = {2013 Elsevier Masson SAS.},
abstract = {A new coumarin-based 'turn-off' fluorescent probe, 7-(diethylamino)-N-(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)-2-oxo-2H-chromene-3-carboxamide (AGD) was synthesized. This compound is highly selective for ferrous ions (Fe2+) and can reversibly detect them in aqueous medium. The probe localizes to the cell membrane in living cells, where it can detect changes in Fe2+ concentration. Molecular dynamics (MD) simulations indicate that AGD interacts with the lipid bilayer at the level of the glycerol moieties.},
keywords = {cells, chelatable chelators, chemosensor, deficiency, dynamics, fe2+ fe3+ fluorescent ion, iron, labile molecular probes, sensor, turn-off},
pubstate = {published},
tppubtype = {article}
}