Publicaciones 2011-2020

@article{RN125,
title = {Design, Synthesis and Cellular Dynamics Studies in Membranes of a New Coumarin-Based "Turn-Off" Fluorescent Probe Selective for Fe2+},
author = { O. Garcia-Beltran and N. Mena and O. Yanez and J. Caballero and V. Vargas and M. Nunez and B.K. Cassels},
url = {/brokenurl#<Go to ISI>://WOS:000325121800007},
doi = {10.1016/j.ejmech.2013.06.022},
issn = {0223-5234},
year = {2013},
date = {2013-01-01},
journal = {European Journal of Medicinal Chemistry},
volume = {67},
pages = {60-63},
publisher = {2013 Elsevier Masson SAS.},
abstract = {A new coumarin-based 'turn-off' fluorescent probe, 7-(diethylamino)-N-(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)-2-oxo-2H-chromene-3-carboxamide (AGD) was synthesized. This compound is highly selective for ferrous ions (Fe2+) and can reversibly detect them in aqueous medium. The probe localizes to the cell membrane in living cells, where it can detect changes in Fe2+ concentration. Molecular dynamics (MD) simulations indicate that AGD interacts with the lipid bilayer at the level of the glycerol moieties.},
keywords = {cells, chelatable chelators, chemosensor, deficiency, dynamics, fe2+ fe3+ fluorescent ion, iron, labile molecular probes, sensor, turn-off},
pubstate = {published},
tppubtype = {article}
}