Publicaciones 2011-2020

@article{RN232,
title = {Determination of Oxytetracycline from Salmon Muscle and Skin by Derivative Spectrophotometry},
author = { M.I. Toral and T. Sabay and S.L. Orellana and P. Richter},
url = {/brokenurl#<Go to ISI>://WOS:000356903400004},
doi = {10.5740/jaoacint.14-027},
issn = {1060-3271},
year = {2015},
date = {2015-01-01},
journal = {Journal of Aoac International},
volume = {98},
number = {3},
pages = {559-565},
abstract = {A method was developed for the identification and quantification of oxytetracycline residues present in salmon muscle and skin using UV-Vis derivative spectrophotometry. With this method, it was possible to reduce the number of steps in the procedure typically required for instrumental analysis of a sample. The spectral variables, order of the derivative, scale factor, smoothing factor, and analytical wavelength were optimized using standard solutions of oxytetracycline dissolved in 900 mg/L oxalic acid in methanol. The matrix effect was significant; therefore, quantification for oxytetracycline residues was carried out using drug-free salmon muscle and skin samples fortified with oxytetracycline. The LOD and LOQ were found to be 271 and 903 mu g/kg, respectively. The precision and accuracy of the method were validated using drug-free salmon muscle and skin tissues fortified at three different concentrations (8, 16, and 32 mg/kg) on 3 different days. The recoveries at all fortified concentrations were between 90 and 105%, and RSDs in all cases were less than 6.5%. This method can be used to screen out compliant samples and thereby reduce the number of suspect positive samples that will require further confirmatory analysis.},
keywords = {antibiotics, aquaculture, detection, fluorescence liquid-chromatography, performance residues, samples tetracycline},
pubstate = {published},
tppubtype = {article}
}

@article{RN20j,
title = {Extraction and Determination of Oxytetracycline Hydrochloride and Oxolinic Acid in Fish Feed by Derivative Spectrophotometry of First Order},
author = { M.I. Toral and S.L. Orellana and C.A. Soto and P. Richter},
url = {/brokenurl#<Go to ISI>://WOS:000296883500006},
doi = {10.1007/s12161-011-9195-3},
issn = {1936-9751},
year = {2011},
date = {2011-01-01},
journal = {Food Analytical Methods},
volume = {4},
number = {4},
pages = {497-504},
abstract = {In this work is proposed the extraction and determination of oxytetracycline (OTC) and oxolinic acid (OA) in fish feed by first-derivative spectrophotometry. The extractions are carried out by parallel modality, where OTC is extracted in the presence of OA in a sample, and in another is extracted OA in the presence of OTC, and the sequential modality, where OTC is extracted first and then followed by OA in a single feed sample. A phosphate buffer, pH 7.0, was selected for OTC extraction and acetonitrile for OA extraction. These solvents were used in both extraction modalities. The extraction percentages obtained by parallel mode are better than those obtained by sequential extraction. In both cases, the limits of extraction were 25 mg kg(-1) for OTC and 10 mg kg(-1) for OA. However, it is proposed to work with the parallel extraction for its efficiency, accuracy, precision, and less time requirement.},
keywords = {animal antibiotics, chlortetracycline, derivative detection, extractions, feed, feeds, flumequine, fluorescence liquid-chromatography, oxolinic oxytetracycline, performance premixes, products, seawater spectrophotometry, tetracycline water},
pubstate = {published},
tppubtype = {article}
}