Publicaciones 2011-2020

@article{RN55,
title = {Adsorption of Fungicides in Chilean Soils Incubated with Biosolids},
author = { S. Copaja and H. Bravo and P. Munoz},
url = {/brokenurl#<Go to ISI>://WOS:000305169800006},
doi = {0.4067/S0717-97072012000200006},
issn = {0717-9707},
year = {2012},
date = {2012-01-01},
journal = {Journal of the Chilean Chemical Society},
volume = {57},
number = {2},
pages = {1091-1094},
abstract = {The efficiency of the adsorption process of the fungicides Captan and Thiram was studied in four Chilean soils from the VI [O'Higgins, (HGS)], VII [Talearehue, (THL)] VIII [Diguillin, (DIG)] and Metropolitan [Maipo, (MAO)] regions of Chile. Changes in the efficiency of adsorption when the natural soils were incubated with biosolids were analyzed., The values of parameters Kf and n from the Freundlich equation indicated an increase in the adsorption of fungicides incubated with biosolids (1% and 10%) with respect to natural soil. A high Kf value (12.1) for DIG-Thiram and a lower Kf value (4.3) for MAO-Captan interaction were observed for natural soils, while in soils incubated with biosolids (10%) the greatest value was (20.3) for DIG-Thiram and the lowest Kf value (10.2) for MAO-Captan. In general the high la values for Caplan and Thiram were correlated with organic carbon content in the natural and incubated soils, except for the interaction THL-Thiram, in which inorganic compounds of soils (clay) were dominant., The distribution constant between solid-liquid phases (Kd) increased in soils incubated with biosolids; the magnitude of this constant was more significant with Thiram. The same behavior was observed for the constant related to organic carbon constants (Koc)., The results of this work confirm that amending soils with biosolids is beneficial for immobilizing fungicides and helps prevent the percolation of Caplan and Thiram through the soil profile and into groundwater},
keywords = {biosolids, captan, degradation, desorption, dissolved fungicide, hplc, mobility, organic-matter, pesticides, sludge, soil, sorption, thiram thiram},
pubstate = {published},
tppubtype = {article}
}

@article{RN36h,
title = {A Preparative Method for the Purification of Isopenicillin N from Genetically Blocked Acremonium Chrysogenum Strain Td189: Studies on the Degradation Kinetics and Storage Conditions},
author = { I. Vaca and J. Casqueiro and R.V. Ullan and A. Rumbero and R. Chavez and J.F. Martin},
url = {/brokenurl#<Go to ISI>://WOS:000292090800006},
doi = {10.1038/ja.2011.30},
issn = {0021-8820},
year = {2011},
date = {2011-01-01},
journal = {Journal of Antibiotics},
volume = {64},
number = {6},
pages = {447-451},
abstract = {A protocol for preparative isopenicillin N (IPN) purification, a highly interesting and hitherto unavailable intermediate of the penicillin and cephalosporin biosynthetic pathway due to its high unstability, is described. Culture broths of Acremonium chrysogenum TD189, a strain blocked in cephalosporin biosynthesis that accumulates this metabolite, were treated with acetone and filtered though charcoal and a hydrophobic resin in a single step as tandem columns. The cleared broth was then lyophilized and passed though a Sephadex G-25 column. The last step was the purification to homogeneity of IPN in a semipreparative HPLC equipment and, optionally, a desalting step by Sephadex G-10 column. Once purified, a complete analysis of the stability of the compound and the conditions for its long-term storage was carried out. Our results suggest a first-order model for IPN decomposition for all the pH and temperature analyzed. IPN is more stable at neutral pH, and once lyophilized, can be stored under vacuum and -75 degrees C with a half-life of 770 days. The Journal of Antibiotics (2011); published online 27 April 2011},
keywords = {biosynthesis, cephalosporin-c, chrysogenum, conversion, hplc, isopenicillin liquid-chromatography n, natural-products, penicillium-chrysogenum, purification, stability, storage, system temperature},
pubstate = {published},
tppubtype = {article}
}