Publicaciones 2011-2020

@article{RN334,
title = {Metabolomic Analysis of Two Parmotrema Lichens: P-Robustum (Degel.) Hale and P-Andinum (Mull. Arg.) Hale Using Uhplc-Esi-Ot-Ms-Ms},
author = { A. Torres-Benitez and M. Rivera-Montalvo and B. Sepulveda and O.N. Castro and E. Nagles and M.J. Simirgiotis and O. Garcia-Beltran and C. Areche},
url = {/brokenurl#<Go to ISI>://WOS:000416528400063},
doi = {10.3390/molecules22111861},
issn = {1420-3049},
year = {2017},
date = {2017-01-01},
journal = {Molecules},
volume = {22},
number = {11},
abstract = {Lichens are symbiotic associations of fungi with microalgae and/or cyanobacteria. Lichens belonging to the Parmeliaceae family comprise 2700 species of lichens, including the Parmotrema genus which is composed of 300 species. The metabolites of this genus include depsides, depsidones, phenolics, polysaccharides, lipids, diphenylethers and dibenzofurans, which are responsible for the biological activities reported including antidiabetic, antihelmintic, anticancer, antioxidant, antibacterial, anti-inflammatory, antimitotic, antitumoral, antifungal, and antioxidant enzyme inhibitory. Due to scarce knowledge of metabolomic profiles of Parmotrema species (P. andinum and P. robustum), a full metabolome study based on ultra-high performance liquid chromatography- diode array detector-electrospray ionization-quadrupole-orbitrap-mass-spectrometry (UHPLC-DAD-ESI-Q-orbitrap MS) was performed for a comprehensive characterization of their substances. From the methanolic extracts of these species, a total of 54 metabolites were identified for the first time using this hyphenated technique, including thirty compounds in P. andinum, and thirty-seven in P. robustum. Moreover, two compounds were not identified as known compounds, and could be new structures, according to our data. This report shows that this technique is effective and accurate for rapid chemical identification of lichen substances and the compounds identified could serve as chemotaxonomic markers to differentiate these ruffle lichens.},
keywords = {constituents, electrospray, lichens, metabolites, metabolomic, ms/ms, nyl. orbitrap, parmotrema, phenolic-compounds, secondary uhplc-ms-ms},
pubstate = {published},
tppubtype = {article}
}

@article{RN184,
title = {Coumarins Isolated from Esenbeckia Alata (Rutaceae)},
author = { O. Garcia-Beltran and C. Areche and B.K. Cassels and L.E.C. Suarez},
url = {/brokenurl#<Go to ISI>://WOS:000334138500008},
doi = {10.1016/j.bse.2013.12.011},
issn = {0305-1978},
year = {2014},
date = {2014-01-01},
journal = {Biochemical Systematics and Ecology},
volume = {52},
pages = {38-40},
keywords = {alata, alkaloids, argentine chemotaxonomy, constituents, derivatives, esenbeckia febrifuga, furocoumarins, grandiflora, limonoids, noncoding plants, regions, rutaceae, terpenes},
pubstate = {published},
tppubtype = {article}
}

@article{RN10b,
title = {Chemistry and Bioactivity of Haplopappus Remyanus ("Bailahuen"), a Chilean Medicinal Plant},
author = { F. Faini and R. Torres and J.M. Rodilla and C. Labbe and C. Delporte and F. Jana},
url = {/brokenurl#<Go to ISI>://WOS:000299000600014},
doi = {10.1590/S0103-50532011001200015},
issn = {0103-5053},
year = {2011},
date = {2011-01-01},
journal = {Journal of the Brazilian Chemical Society},
volume = {22},
number = {12},
pages = {2344-U2134},
abstract = {Chromatography on the resinous extract of aerial parts of Haplopappus remyanus led to the isolation of 18-acetoxy-labda-7,13E-dien-15-oic acid along with the monoterpene derivatives 9-hydroxy-alpha-terpineol, 9-benzoyloxy-alpha-terpineol, 7-hydroxy-9-benzoyloxy-alpha-terpineol and 9-benzoyloxy-(1-formyl)-alpha-terpineol. Structures for the new compounds are proposed on spectroscopic evidence. The presence of quercetin and five other known flavonoids identified in this study could account for the reported high antioxidant activity and the moderate topic anti-inflammatory effect on induced ear oedema. MTT assay with CCRF-CEM tumor cells showed 50% of the cytotoxic activity displayed by doxorubicin under the same conditions. Quantitative differences in chemical composition were detected in comparison with previous studies of the species that could be attributed to environmental factors.},
keywords = {anti-inflammatory antioxidant, arachidonic-acid, constituents, cytotoxic esters, exudate, flavonoids, haplopappus inflammation remyanus, resinous},
pubstate = {published},
tppubtype = {article}
}